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Table 2 Study characteristics of the included systematic reviews and meta-analyses

From: Association between work-related biomechanical risk factors and the occurrence of carpal tunnel syndrome: an overview of systematic reviews and a meta-analysis of current research

Author, year Analysis AMSTAR-R grade Country Years included No. of studies included Study designs A priori quality criteria The study’s aim was to …
You et al. 2014 [43] MA C US 1980–2012 n = 8 CC = 2; CS = 6 Recognition of bias by sensitivity analysis ... conduct a meta-analysis of existing studies to evaluate the evidence of the relationship between wrist posture at work and CTS
Mediouni et al. 2014 [42] MA B FR 1992–2012 n = 6 C = 2; CS = 4 Strengths and limitations acknowledged ... conduct a systematic review and meta-analysis of the available epidemiological data on the association between computer work exposure and CTS
Barcenilla et al. 2012 [41] MA B AU 1980–2009 n = 37 C = 3; CC = 5; CS = 28 Risk of Bias Tool ... examine the association between workplace exposure and CTS by meta-analysis, with respect to exposure to hand force, repetition, vibration and wrist posture
Spahn et al. 2012 (in German) [31] MA C DE ≤2011 n = 55 n/a n/a ... conduct a systematic review and meta-analysis to identify associated and risk factors for CTS in the occupational setting
Van Rijn et al. 2009 [35] SR B NL 1966–2007 n = 44 C = 5; CC = 9; CS = 30 16-item score ... provide a quantitative assessment of the exposure-response relationship between work-related physical and psychosocial factors and the occurrence of CTS in occupational populations
Lozano-Calderón et al. 2008 [46] SR D US ≤2008 n = 51a; n = 33b; (total = 66) C = 7a; CC = 12a; C = 29a; Other = 3a Bradford Hill criteria for causation ... evaluate the quality and strength of scientific evidence supporting an aetiological relationship between a disease and a proposed risk factor, using a scoring system based on the Bradford Hill criteria for causal association – example of CTS
Thomsen et al. 2008 [45] SR C DK ≤2004 n = 8 C = 4; CC = 2; CS = 2 Selected criteria (4 main domains) ... conduct a systematic review to examine evidence for an association between computer work and CTS
Palmer et al. 2007 [22] SR C GB ≤2004 n = 38 n/a n/a ... conduct a systematic review to assess occupational risk factors for CTS
Sulsky et al. 2005 [44] SR C DE 1997–2003 n = 34 C = 10; CC = 2; CS = 22 Selected criteria (6 main domains) ... clarify the relationship between CTS and occupation using quality based criteria from the epidemiological literature
Abbas et al. 1998 [21] MA D US 1980–1995 n = 17 C = 3; CC = 4; CS = 10 n/a ... conduct a meta-analysis on work-related CTS and to identify risk estimates and possible biases influencing the risk estimates
  1. Abbreviations: AMSTAR-R Assessment of Multiple Systematic Reviews – Revised (numeric quality score in grades: A = 37–44; B = 29–36; C = 21-28; D = 13–20 points), C Cohort, CC Case control, CS Cross-sectional, CTS Carpal tunnel syndrome, MA Meta-analysis, SR Systematic review
  2. aStudies investigating occupational factors alone
  3. bStudies investigating both biological and occupational factors