Treatment parameter | N = 865 |
---|---|
Previous treatments | |
Number of prior DMARDs | N = 865 |
0–3, n (%) | 582 (67.3) |
>3, n (%) | 283 (32.7) |
Number of prior anti-TNF agents | N = 865 |
≥2, n (%) | 429 (49.6) |
<2, n (%) | 436 (50.4) |
Type of biologic agent | N = 851 |
Other MOA, n (%) | 134 (15.8) |
Anti-TNF agent | 717 (84.3) |
Reason for discontinuation of last biologic | N = 847 |
Intolerance, n (%) | 190 (22.4) |
Primary inefficacy, n (%)a | 203 (24.0) |
Secondary inefficacy, n (%)† | 400 (47.2) |
Major improvement + other reasons, n (%) | 54 (6.4) |
Concomitant therapies | |
Abatacept treatment pattern at initiation | N = 865 |
Monotherapy, n (%) | 201 (23.2) |
Combination with MTX (± other DMARDs), n (%) | 483 (55.8) |
Combination with other DMARDs, n (%) | 181 (20.9) |
Corticosteroid treatment pattern at abatacept initiation (versus before initiation)‡ | N = 865 |
No corticosteroids, n (%) | 202 (25.4) |
Continuous use of corticosteroids, n (%) | 491 (56.8) |
Stop corticosteroid use, n (%) | 18 (2.1) |
Introduction of corticosteroids, n (%) | 154 (17.8) |