Fig. 4

Effect of anti-CCP and RF positivity on the phagocytosis of opsonized yeast cells by monocytes from RA patients. Data are expressed as medians, quartiles and extreme values. RA caused an increase in the phagocytosis of opsonized yeast (p < 0.001; t test with Welch’s correction), but no difference was observed between anti-CCP- or RF-negative or -positive individuals (p > 0.05). Top: monocyte phagocytic index (a, b, c); Middle: number of S. cerevisiae yeast cells phagocytosed by monocyte (d, e, f); Bottom: percent of monocytes engaged in phagocytosis (g, h, i). The statistical differences are marked in the graphics and in text