Fig. 2

Effect of anti-CCP and RF positivity on the phagocytosis of non-opsonized yeast cells by monocytes from RA patients. Data are expressed as medians, quartiles and extreme values. RA caused a rise in the phagocytosis of non-opsonized yeasts (p < 0.0009; t test with Welch’s correction), but no difference was observed between anti-CCP- or RF-negative or -positive individuals (p > 0.05). Top: monocyte phagocytic index (a, b, c); Middle: average number of S. cerevisiae yeast cells ingested by phagocytosing monocyte (d, e, f); Bottom: percent of monocytes engaged in phagocytosis (g, h, i). The statistical differences are marked in the graphics and in text