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Table 1 Concentrations of the cells and molecules evaluated in whole blood, both platelet rich gel (PRG) supernatants and synovial fluida

From: Effects over time of two platelet gel supernatants on growth factor, cytokine and hyaluronan concentrations in normal synovial membrane explants challenged with lipopolysaccharide

 

Fluid

Variable

Whole blood

L-PRG

P-PRG

Synovial fluid

Platelet ×103/μL

124.7 ± 3.1

311.6 ± 20.4b

99.4 ± 4.3c

ND

WBC ×103/μL

8.4 ± 3.6

34.2 ± 3.7b

0.13 ± 0.03c

ND

RBC ×106//μL

6.31 ± 0.3

1.6 ± 0.4b

0.02 ± 0.01c

ND

TGF-β1 (pg/mL)

ND

1669.2 ± 313.2

1369.2 ± 21.4

1413.8 ± 4.8

PDGF-BB (pg/mL)

ND

3069. 9 ± 1261.6

383.8 ± 80.9b

60.5 ± 0.9b

TNF-α (pg/mL)

ND

60 ± 0.5b,c

59 ± 1.4b

66.7 ± 3.3c

IL-4 (pg/mL)

ND

75.7 ± 9.3b

61.1 ± 1.52b

101.8 ± 33.7c

IL-1ra (pg/mL)

ND

160.4 ± 68.0

58.7 ± 3.1b

77.8 ± 10.7

Hyaluronic acid (ng/mL)

ND

6.9 ± 2.9

2.3 ± 1.08

53017.6 ± 12140b

  1. a Data are presented as means (m.s.e).b-c Lowercase letters denote significant differences (p < 0.01) between groups in the same row by Tukey test. ND: no determined