Table 1 Descriptive baseline characteristics of Greek patients enrolled in ExFOS and EFOS

Enrolment period (dates of first and last patient enrolment)

16 Feb 2011 – 24 May 2012

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05 Jul 2004 – 30 Sep 2005

Enrolment rate (patients/site/month)

0.95

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0.65

Number of patients (% women)

439 (92.3)

34

405

302 (100)

Mean (SD) age (years)

70.1 (9.8)

71.5 (10.3)

70.0 (9.8)

70.0 (8.5)

Mean (SD) BMI (kg/m²)

26.7 (4.3)

26.4 (4.6)

26.7 (4.3)

26.3 (4.0)

Mean (SD) time since menopause (years)

-

-

22.1 (10.3)

24.4 (9.0)

Mean (SD) fertile period (years)

-

-

34.6 (5.6)

32.4 (5.9)

Early menopause before age 40 years (% patients)

-

-

5.5

9.3

Current smokers

12.1

33.3

10.4

12.6

No exercise

49.2

61.8

48.1

71.5

Hip fracture in biological mother

18.1

14.8

18.4

16.6

One or more falls in the preceding year

37.1

50.0

36.0

40.7

Assist standing using arms

41.3

58.8

39.8

92.1

Mean (SD) DXA BMD spine

−3.4 (0.7)

−3.3 (1.3)

−3.4 (0.7)

−3.4 (0.7)

Mean (SD) DXA BMD total hip (higher N included)

−3.2 (0.5)

−3.4 (0.6)

−3.2 (0.5)

−2.8 (1.1)

Mean (SD) DXA BMD femoral neck (higher N included)

−2.8 (1.2

−3.0 (0.4)

−2.8 (1.2)

−3.1 (0.8)

Fracture history (% patients)

55.1

70.6

53.8

74.5 ^a

Mean (SD) fracture number (for patients with at least one fracture)

1.7 (1.1)

2.0 (1.9)

1.7 (1.0)

1.8 (1.4)

Patients with vertebral fractures (% patients)

38.7

50

37.8

59.6 ^b

Patients with vertebral fractures (% of patients with fractures)

70.2

70.8

70.2

85.9

Patients with hip fractures (% of patients with fractures)

8.3

20.8

6.9

2.7

Prior anti-osteoporotic treatments

80.2

55.9

82.2

83.1

Calcitonin

23.2^c

5.9

24.7

64.6

Bisphosphonates

59.0^c

32.4

61.2

36.1

Prior glucocorticoid use

8.9^c

17.6

8.1

14.6

Back pain in the previous year (% patients)

88.4

76.5

89.4

97.4

Moderate to severe pain in the month before enrolment (% patients)

80.9

88.0

80.4

85.3

Mean (SD) EQ-5D VAS (cm)

57.0 (21.7)

56.9 (20.7)

57.0 (21.8)

54.2 (24.9)