Fig. 1

Experimental design to identify capsule genes associated with immobilization-induced joint contractures. After preprocessing raw microarray data, intensity values of probe sets measured at 2, 4, 8, and 16 weeks were compared to results measured at week 1 to determine the fold change in expression. Probe sets counts were separated into four bins: up-regulated by a fold change of 1.5 to 2.0 or above 2.0, and down-regulated by a fold change of −1.5 to −2 or more than −2. The number of probe sets included in each bin is indicated on the Y axis for individual time points indicated on the X axis