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Table 2 ANA profiles of patients with systemic autoimmune diseases

From: Screening for IgG4-type anti-nuclear antibodies in IgG4-related disease

Case

ANA

Specific autoantibodies

IgG4a

IgGa

SLE 1b

Spe 320

dsDNA, ssDNA, U1-RNP, Sm

21.3

1830

SLE 2

Homo + Spe 320

dsDNA, ssDNA, SS-A

11

826

SLE 3

Spe 1280

dsDNA, ssDNA, Sm, Ribosome

20

2043

SLE 4

Spe 640

ssDNA, U1-RNP, Sm, SS-A, SS-B

8.3

829

SLE 5

Homo + Spe 1280

dsDNA, ssDNA, U1-RNP, Sm, SS-A, SS-B

7

556

SLE 6

Homo + Spe 160

ssDNA

48.6

1938

SLE 7

Spe 320

dsDNA, SS-A

19.6

1186

SLE 8

Spe 5120

dsDNA, ssDNA, U1-RNP, Sm, SS-A

7

908

SSc 1

Discrete spe 1280

Centromere

7

1177

SSc 2b

Discrete spe 1280, Spe 160, Cyto 80

Centromere, SS-A

21.2

1772

SSc 3

Spe 1280

Scl-70, U1-RNP, SS-A

25.5

2147

SSc 4

Discrete spe 1280

Centromere, Scl-70, U1-RNP

12.4

1108

SS 1

Spe 320

SS-A, SS-B

33.4

2974

SS 2

Spe 160

SS-A, SS-B

16.5

1765

SS 3

Spe 80

SS-A, SS-B

74

1370

SS 4c

Spe 640

SS-A

228

1721

SS 5

Spe 40, Cyto 80

SS-A

38

2133

SS 6

Spe 160

SS-A, SS-B

14.5

2340

SS 7

Spe 160

SS-A, SS-B

9.5

1882

SS 8b

Spe + Nucleolar 80, Cyto 40

SS-A

20.1

1678

PM 1

Spe + Nucleolar 640

Ku

53.5

1668

PM 2b

Spe 320, Cyto 40

ssDNA, U1-RNP, Sm, SS-A

12.9

1132

PM 3

Spe 40, Cyto 160

PL-7

15

717

PM 4

Spe 320

U1-RNP, Sm

5

282

PM 5

Spe 1280

Ku, SS-A, SS-B

<3

823

PM 6

Spe 40, Cyto 80

SRP

18.4

1365

PM 7

Homo + Spe 160

Not detected

19

2051

  1. amg/dL in serum. bShown in Fig. 3. cShown in Fig. 4
  2. ANA: anti-nuclear antibody; Cyto: cytoplasmic; Discrete spe: discrete speckled; Homo: homogeneous; RNP: ribonucleoprotein; Spe: speckled; SRP: signal recognition particle