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Table 2 ANA profiles of patients with systemic autoimmune diseases

From: Screening for IgG4-type anti-nuclear antibodies in IgG4-related disease

Case ANA Specific autoantibodies IgG4a IgGa
SLE 1b Spe 320 dsDNA, ssDNA, U1-RNP, Sm 21.3 1830
SLE 2 Homo + Spe 320 dsDNA, ssDNA, SS-A 11 826
SLE 3 Spe 1280 dsDNA, ssDNA, Sm, Ribosome 20 2043
SLE 4 Spe 640 ssDNA, U1-RNP, Sm, SS-A, SS-B 8.3 829
SLE 5 Homo + Spe 1280 dsDNA, ssDNA, U1-RNP, Sm, SS-A, SS-B 7 556
SLE 6 Homo + Spe 160 ssDNA 48.6 1938
SLE 7 Spe 320 dsDNA, SS-A 19.6 1186
SLE 8 Spe 5120 dsDNA, ssDNA, U1-RNP, Sm, SS-A 7 908
SSc 1 Discrete spe 1280 Centromere 7 1177
SSc 2b Discrete spe 1280, Spe 160, Cyto 80 Centromere, SS-A 21.2 1772
SSc 3 Spe 1280 Scl-70, U1-RNP, SS-A 25.5 2147
SSc 4 Discrete spe 1280 Centromere, Scl-70, U1-RNP 12.4 1108
SS 1 Spe 320 SS-A, SS-B 33.4 2974
SS 2 Spe 160 SS-A, SS-B 16.5 1765
SS 3 Spe 80 SS-A, SS-B 74 1370
SS 4c Spe 640 SS-A 228 1721
SS 5 Spe 40, Cyto 80 SS-A 38 2133
SS 6 Spe 160 SS-A, SS-B 14.5 2340
SS 7 Spe 160 SS-A, SS-B 9.5 1882
SS 8b Spe + Nucleolar 80, Cyto 40 SS-A 20.1 1678
PM 1 Spe + Nucleolar 640 Ku 53.5 1668
PM 2b Spe 320, Cyto 40 ssDNA, U1-RNP, Sm, SS-A 12.9 1132
PM 3 Spe 40, Cyto 160 PL-7 15 717
PM 4 Spe 320 U1-RNP, Sm 5 282
PM 5 Spe 1280 Ku, SS-A, SS-B <3 823
PM 6 Spe 40, Cyto 80 SRP 18.4 1365
PM 7 Homo + Spe 160 Not detected 19 2051
  1. amg/dL in serum. bShown in Fig. 3. cShown in Fig. 4
  2. ANA: anti-nuclear antibody; Cyto: cytoplasmic; Discrete spe: discrete speckled; Homo: homogeneous; RNP: ribonucleoprotein; Spe: speckled; SRP: signal recognition particle