All N = 75488 | With tamoxifen N = 50257 | Without tamoxifen N = 25231 | |||||
---|---|---|---|---|---|---|---|
Variable | n | % | n | % | n | % | p-value |
Age, years | <0.0001 | ||||||
<50 | 35715 | 47.3 | 25778 | 51.3 | 9937 | 39.4 | |
50-59 | 21676 | 28.7 | 13124 | 26.1 | 8552 | 33.9 | |
60-69 | 11353 | 15.0 | 7001 | 13.9 | 4352 | 17.6 | |
70+ | 6744 | 8.93 | 4354 | 8.66 | 2390 | 9.47 | |
Urbanization | 0.34 | ||||||
Urban | 50793 | 67.3 | 33874 | 67.4 | 16919 | 67.1 | |
Rural | 24695 | 32.7 | 16383 | 32.6 | 8312 | 32.9 | |
Month income, NTD | <0.0001 | ||||||
<= 15000 | 12795 | 17.0 | 8231 | 16.4 | 4564 | 18.1 | |
15001-20000 | 39463 | 52.3 | 26326 | 52.4 | 13137 | 52.1 | |
>20000 | 33230 | 30.8 | 15700 | 31.2 | 7530 | 29.8 | |
Comorbidity | |||||||
Hypertension | 21882 | 29.0 | 14142 | 28.1 | 7740 | 30.7 | <0.0001 |
Hyperlipidemia | 15458 | 20.5 | 9952 | 19.8 | 5506 | 21.8 | <0.0001 |
Diabetes | 8948 | 11.9 | 5698 | 11.3 | 3250 | 12.9 | <0.0001 |
PAD | 1477 | 1.96 | 905 | 1.80 | 572 | 2.27 | <0.0001 |
Stroke | 1715 | 2.27 | 1012 | 2.01 | 703 | 2.79 | <0.0001 |
Osteoporosis | 8024 | 10.6 | 5114 | 10.2 | 2910 | 11.5 | <0.0001 |
Medicine, n (%) | |||||||
HRT used before the index date | 36690 | 48.6 | 24487 | 48.7 | 12203 | 48.4 | 0.35 |
Aromatase inhibitors used before the end point | 20507 | 27.2 | 16273 | 32.4 | 4234 | 16.8 | <0.0001 |