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Table 2 Changes of DXR-parameters between baseline and month 22 for the leflunomide and methotrexate group

From: Is there a role for Digital X-ray Radiogrammetry as surrogate marker for radiological progression and imaging of structural integrity in rheumatoid arthritis?

Group

 

Baseline

Month 22

Difference

Relative change

p-value

mean (SD)

mean (SD)

mean (SD)

  

Leflunomide

DXR-BMD in g/cm2

0.569 (0.088)

0.561 (0.094)

−0.008 (0.024)

- 1.4 %

p < 0.05

DXR-MCI

0.452 (0.095)

0.442 (0.098)

−0.010 (0.022)

- 2.2 %

p < 0.05

DXR-CT in cm

0.185 (0.038)

0.181 (0.040)

−0.004 (0.009)

- 2.2 %

p < 0.05

DXR-Win cm

0.822 (0.073)

0.823 (0.073)

0.001 (0.006)

+0.1 %

p = n. s.

Methotrexate

DXR-BMD in g/cm2

0.578 (0.070)

0.553 (0.080)

−0.024 (0.037)

- 4.3 %

p < 0.05

DXR-MCI

0.447 (0.076)

0.425 (0.078)

−0.022 (0.027)

- 4.9 %

p < 0.05

DXR-CT in cm

0.186 (0.029)

0.176 (0.032)

−0.010 (0.014)

- 5.4 %

p < 0.05

DXR-in cm

0.840 (0.086

0.835 (0.093)

−0.005 (0.031)

- 0.6 %

p = n. s.

  1. Notes: DXR = Digital X-ray Radiogrammetry
  2. BMD = Bone Mineral Density
  3. MCI = Metacarpal Index
  4. CT = Cortical Thickness
  5. W = Metacarpal Bone Width
  6. SD = Standard Deviation
  7. n. s. = not significant