Glutaraldehyde cross-linked albumin
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BioGlue
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Sealant
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Glutaraldehyde cross-links bovine albumin to cell proteins at wound site to form a tough scaffold [2].
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Fibrin sealant (human)
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Evicel
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Sealant, hemostatic agent
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Thrombin and fibrinogen mixed at site of application; thrombin cleaves fibrinogen to clot-forming fibrin [2].
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Butyl lactoyl cyanoacrylate
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Omnex
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Adhesive
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Liquid monomers that rapidly form polymers in the presence of water and thereby quickly glue surfaces together [2].
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2-octyl cyanoacrylate
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Dermabond
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Adhesive
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Liquid monomers that rapidly form polymers in the presence of water and thereby quickly glue surfaces together [2].
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Lysine-based dendritic hydrogel (PEG-LysNH2)
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Not available
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Sealant
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The cross-linked hydrogel forms an adhesive physical barrier on the wound’s surface [5] - hemostasis is not dependent on the clotting cascade.
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