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Table 1 Baseline characteristics of human immunodeficiency virus (HIV)/chronic hepatitis C virus (HCV)-coinfected, chronic HCV-monoinfected, and HIV-monoinfected participants

From: Prevalence and risk factors for patient-reported joint pain among patients with HIV/Hepatitis C coinfection, Hepatitis C monoinfection, and HIV monoinfection

 

HCV/HIV-

HCV-

HIV-

P-value*

 

Coinfected

Monoinfected

Monoinfected

HCV/HIV

HCV/HI

 

N = 79

N = 93

N = 30

vs HCV

V vs HIV

Site (n, %)

   

<0.001

<0.001

HUP

2 (3%)

35 (38%)

0 (0%)

  

PPMC

35 (44%)

20 (22%)

1 (3%)

  

PVAMC

42 (53%)

38 (41%)

29 (97%)

  

Age (Median, IQR)

55 (43–64)

57.5 (53.5-61)

54 (51–60)

0.04

NS

Sex (n, %)

   

NS

NS

Male

68 (86%)

77 (83%)

28 (93%)

  

Female

11 (14%)

16 (17%)

2 (7%)

  

Race (n, %)

   

0.001

NS

Caucasian

9 (11%)

35 (38%)

5 (17%)

  

Black

64 (81%)

50 (54%)

24 (80%)

  

Hispanic

4 (5%)

3 (3%)

0 (0%)

  

Other

2 (3%)

2 (2%)

1 (3%)

  

BMI (kg/m2)

25.0

29.2

27.2

<0.001

0.05

Median (IQR)

(22.5-29.0)

(25.5-33.2)

(25.0-33.2)

  

Current smoker (n, %)

29 (37%)

37 (40%)

9 (30%)

NS

NS

HCV Treatment (n, %)

   

0.01

N/A

Current

4 (5%)

17 (18%)

0 (0%)

  

Past

22 (28%)

31 (33%)

0 (0%)

  

Never

53 (67%)

45 (48%)

30 (100%)

  

HCV Genotype (n, %)

   

NS

N/A

1 (A or B)

70 (89%)

60 (65%)

0 (0%)

  

2

1 (1%)

5 (5%)

0 (0%)

  

3

1 (1%)

4 (4%)

0 (0%)

  

HCV RNA (IU/mL)

1.37

0.62

N/A

0.02

N/A

Median in million (IQR)

(0.44-4.63)

(0.03-2.70)

   

CD4 count (cells/mm3)

474

N/A

480

N/A

NS

Median (IQR)

(358–666)

 

(295–673)

  

Antiretroviral

67 (85%)

0 (%)

26 (87%)

N/A

NS

therapy (n, %)

     

Previous arthritis diagnosis (n, %)

37 (40%)

28 (35%)

8 (27%)

NS

NS

Analgesic medication use (n, %)

   

NS

NS

Any

41 (52%)

49 (53%)

20 (67%)

  

Opiate

15 (19%)

15 (16%)

4 (13%)

 

Gabapentin

17 (22%)

11 (12%)

8 (27%)

NSAIDs

21 (27%)

23 (25%)

10 (33%)

Tylenol

10 (13%)

18 (19%)

9 (30%)

  1. Abbreviations: HUP = Hospital of University of Pennsylvania, PPMC = Penn Presbyterian Medical Center, PVAMC = Philadelphia Veterans Affairs Medical Center, BMI = body mass index, NS = Not significant (p > 0.05), N/A = Not Applicable.
  2. Previous arthritis diagnosis included rheumatoid arthritis (N = 4), osteoarthritis (N = 46), ankylosing spondylitis (N = 1), systemic lupus erythematosus (N = 1), and patient reported “arthritis” but unknown type (N = 22). One patient carried more than one diagnosis.
  3. Wilcoxan-rank sum test, remainder of the p-values were calculated using the chi2 test.