Growth factor release by vesicular phospholipid gels: in-vitro results and application for rotator cuff repair in a rat model

Table 1 In-vitro G-CSF Release

Formulation (1 mg)	G-CSF VPGs_1	G-CSF VPGs_2	G-CSF VPGs_3	G-CSF VPGs_4
Lipid content	400 mg/g	450 mg/g	490 mg/g	450 mg/g
G-CSF content	4.0 mg/g	4.0 mg/g	4.0 mg/g	8.4 mg/g
Initial release (Day 1)	64 μg	32 μg	43 μg	49 μg
Daily release amount range	56 μg-388 μg	32 μg-204 μg	32 μg-150 μg	25 μg-76 μg
Average release amount per day	149 μg	88 μg	89 μg	43 μg
Daily release percentage of the incorporated protein/%	3.7%	2.2%	2.2%	0.5%

ISSN: 1471-2474