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Table 1 In-vitro G-CSF Release

From: Growth factor release by vesicular phospholipid gels: in-vitro results and application for rotator cuff repair in a rat model

Formulation (1 mg) G-CSF VPGs_1 G-CSF VPGs_2 G-CSF VPGs_3 G-CSF VPGs_4
Lipid content 400 mg/g 450 mg/g 490 mg/g 450 mg/g
G-CSF content 4.0 mg/g 4.0 mg/g 4.0 mg/g 8.4 mg/g
Initial release (Day 1) 64 μg 32 μg 43 μg 49 μg
Daily release amount range 56 μg-388 μg 32 μg-204 μg 32 μg-150 μg 25 μg-76 μg
Average release amount per day 149 μg 88 μg 89 μg 43 μg
Daily release percentage of the incorporated protein/% 3.7% 2.2% 2.2% 0.5%
  1. Daily release of G-CSF from 1 g VPGs based on various compositions.