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Table 3 Summary of association result

From: A genome-wide association study of copy-number variation identifies putative loci associated with osteoarthritis in Koreans

Chr Start End Length (bp) Gene OA type CNV genotype frequency (%)a OR (95% CI)b Adjusted P-valuec
Cases (0/1/2) Controls (0/1/2)
1 112490851 112509390 18539 Upstream of KCND3 Hand 23.0/52.9/24.0 13.1/52.5/34.5 0.41 (0.25 - 0.68) 5.8 × 10-4
8 9535412 9536779 1367 Intron of TNKS Hand, Knee 2.4/28.8/68.7 4.3/34.5/61.2 1.37 (1.02 - 1.85) 3.5 × 10-2
9 71952096 71953157 1061 Intron of MAMDC2 Knee -/7.2/92.8 -/3.0/97.0 0.36 (0.16 - 0.86) 1.9 × 10-2
11 85981796 85983048 1252 Intron of ME3 Hand 6.9/33.3/59.8 11.1/40.5/48.4 1.70 (1.21 - 2.40) 2.4 × 10-3
13 36971042 36976531 5489 Downstream of POSTN Hand, Knee 2.4/31.3/66.3 1.5/22.5/76.0 0.64 (0.47- 0.87) 4.9 × 10-3
17 47477132 47478158 1026 Intron of CA10 Hand 1.5/19.1/79.4 2.8/26.6/70.7 1.69 (1.14 - 2.55) 1.02 × 10-2
  1. aDesignations for the CNV genotype are as indicated in the Methods. A dash indicates a zero-copy CNV region. ORb and Adjusted P-valuec were adjusted by gender, age, and body mass index; OR: odds ratio, CI: Confidence interval.