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Table 1 Clinimetric, laboratory and ultrasound characteristics of study population at baseline and after 12 months follow-up

From: Hypovitaminosis D in recent onset rheumatoid arthritis is predictive of reduced response to treatment and increased disease activity: a 12 month follow-up study

Patients (N = 37)

Baseline

12 months follow-up

P-value

ESR (mm/h), mean ± SD

31 ± 21

13.9 ± 11

0.0001^

CRP (g/L), mean ± SD

13.6 ± 16

5.81 ± 4.71

0.003^

RF positivity, number (%)

31 (83)

31 (83)

-

APCA positivity, number (%)

30 (81)

30 (8)

-

Morning stiffness (minutes), mean ± SD

62 ± 48

20.8 ± 23

0.0001^

Ritchie index, mean ± SD

10 ± 8.2

2.5 ± 2.9

0.00001^

VAS pain (mm), mean ± SD

63 ± 24

31.9 ± 32

0.002^

VAS disease patient (mm), mean ± SD

58 ± 23

31 ± 27

0.0001^

EGA (mm), mean ± SD

54 ± 20

24.3 ± 20

0.0001^

Number of tender joints (0–44), median (range)

12 (0–35)

2 (0–19)

00001^

Number of swollen joints (0–44), median (range)

5 (0–22)

3 (0–21)

0.0001^

Number of tender joints (0–28), median (range)

8 (0–24)

4 (0–30)

0.0001^

Number of swollen joints (0–28), median (range)

5 (0-20

5 (0–32)

0.0001^

DAS 28 score, mean ± SD

5.18 ± 1

2.77 ± 1.14

0.0001^

Ultrasound Total Synovitis score, mean ± SD

25.7 ± 21.7

8.31 ± 6.2

0.0008^

Ultrasound Total power Doppler score, mean ± SD

3.3 ± 5.9

0.65 ± 1.22

0.005^

Ultrasound Total Erosion score, mean ± SD

1.34 ± 2.7

10.31 ± 9.8

ns^

Patients ≥1 erosion, number (%)

12 (32%)

18 (48%)

ns*

X-Ray Erosion, +ve, number (%)/%

6 (16%)

-

 
  1. Results are shown as mean ± SD, median(min-max) or number(percentage) of patients, as appropriated. ^Wilcoxon test applied, *chi-squared test applied. P-value <0.05 are considered significant. ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; RF, Rheumatoid Factor; ACPA, anti-citrullinated protein antibodies; VAS, visual analogue scale; EGA, examinator’s global disease activity assessment; DAS28, 28-joint disease activity score.