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Table 3 The MLPA probe copy numbers of SMA-related genes in 212 Chinese healthy individuals

From: Molecular characterization and copy number of SMN1, SMN2 and NAIP in Chinese patients with spinal muscular atrophy and unrelated healthy controls

  

MLPA probe copy number

 

Total

SMN1/SMN2

SMN1

SMN2

NAIP

Group

N = 212

Exon1

Exon4

Exon6

Exon8

Exon7

Exon8

Exon7

Exon8

Exon13

Exon5

1

117(55.2%)

4-5

4-5

4

4-5

2

2

2

2

2

2

2

1(0.5%)

4

4

4

4

2

3

2

1

2

2

3

1(0.5%)

4

4-5

4

4

2

1

2

3

2

2

4

54(25.4%)

3-4

3-4

3

3-4

2

2

1

1

2

2

5

1(0.5%)

3

3

3

3

2

3

1-2

0

2

2

6

7(3.3%)

3-4

3

3-4

3-4

2

2

1

1

2

3

7

1(0.5%)

3-4

3-4

3-4

3

2

2

1

1

2

4

8

4(1.9%)

2

2

2

2

2

2

0

0

1

2

9

5(2.3%)

2

2-3

2-3

2-3

2

2

0

0

1

3

10

1(0.5%)

3

3

3-4

3-4

2

2

1

1

1

1

11

5(2.3%)

4

4-5

4

4

2

2

2

2

2

3

12

1(0.5%)

4

4-5

4

4-5

2

1

2

3

2

3

13

2(0.9%)

4

4-5

4

4-5

2

3

2

1

2

3

14

2(0.9%)

4

4

4

4

3

3

1

1

2

2

15

3(1.4%)

4

4-5

4

4-5

2

2

2

2

2

1

16

2(0.9%)

4-5

5

5

4-5

2

2

3

3

2

2

17

1(0.5%)

4

4-5

4

5

1

2

1

2

2

2

18

1(0.5%)

4-5

5

5

4-5

3

3

2

2

2

3

19

1(0.5%)

4-5

5

4-5

5

3

3

2

2

2

1

20

1(0.5%)

3

3-4

3-4

3-4

1

1

2

2

2

1

21

1(0.5%)

4

4

4

4

3

3

1

1

2

3