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Figure 8 | BMC Musculoskeletal Disorders

Figure 8

From: Alterations in the vimentin cytoskeleton in response to single impact load in an in vitro model of cartilage damage in the rat

Figure 8

Photomicrographs of the cartilage from the distal femur of a rat. The photomicrographs illustrate the immunoreactivity of ERK and pERK within the cartilage. Sections 6a and 6b have been immunohistochemically labeled with anti-ERK antisera and visualized with an immunofluorescent secondary antibody (green), sections 6c and d have been immunohistochemically labeled with anti-pERK antisera and visualized with an immunofluorescent secondary antibody. Sections 6a and 6c represent t= 0 and sections 6 b and d represent t = 1 hour. In Figure 6a (ERK, t = 0) there is immunoreactiviey tht is not ssignificantly different from Figure 6b (ERK, t = 1 hour) i.e. there has been no change in ERK immunoreactivity levels. In contrast in Figure 6c (pERK, t = 0) there is no immunoreactivity i.e. no activation of pERK, whilst in Figure 6d (pERK, t = 1 hour) strong immunoreactivity is seen. Scale bar = 13 μm

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