Figure 8From: Alterations in the vimentin cytoskeleton in response to single impact load in an in vitro model of cartilage damage in the rat Photomicrographs of the cartilage from the distal femur of a rat. The photomicrographs illustrate the immunoreactivity of ERK and pERK within the cartilage. Sections 6a and 6b have been immunohistochemically labeled with anti-ERK antisera and visualized with an immunofluorescent secondary antibody (green), sections 6c and d have been immunohistochemically labeled with anti-pERK antisera and visualized with an immunofluorescent secondary antibody. Sections 6a and 6c represent t= 0 and sections 6 b and d represent t = 1 hour. In Figure 6a (ERK, t = 0) there is immunoreactiviey tht is not ssignificantly different from Figure 6b (ERK, t = 1 hour) i.e. there has been no change in ERK immunoreactivity levels. In contrast in Figure 6c (pERK, t = 0) there is no immunoreactivity i.e. no activation of pERK, whilst in Figure 6d (pERK, t = 1 hour) strong immunoreactivity is seen. Scale bar = 13 μmBack to article page