Skip to main content

Advertisement

Table 1 Baseline characteristics

From: Choline-stabilized orthosilicic acid supplementation as an adjunct to Calcium/Vitamin D3 stimulates markers of bone formation in osteopenic females: a randomized, placebo-controlled trial

  Placebo ch-OSA
   3 mg Si 6 mg Si 12 mg Si
AGE (years) 62.0 ± 10.9 (n = 37) 60.4 ± 11.8 (n = 33) 59.7 ± 9.4 (n = 33) 60.8 ± 9.7 (n = 33)
BMI 23.2 ± 3.0 (n = 37) 24.4 ± 3.8 (n = 33) 24.1 ± 4.6 (n = 33) 25.2 ± 3.8 (n = 33)
Menopausal status 6 pre/31 post (n = 37) 6 pre/27 post (n = 33) 5 pre/28 post (n = 33) 4 pre/29 post (n = 33)
BMD     
Spine total (g/cm 2 ) 0.797 ± 0.061 (n = 37) 0.805 ± 0.052 (n = 33) 0.805 ± 0.069 (n = 33) 0.776 ± 0.072b (n = 33)
Femur total (g/cm 2 ) 0.789 ± 0.103 (n = 37) 0.791 ± 0.094 (n = 33) 0.792 ± 0.080 (n = 33) 0.781 ± 0.103 (n = 33)
Femur neck (g/cm 2 ) 0.670 ± 0.085 (n = 37) 0.677 ± 0.085 (n = 33) 0.667 ± 0.079 (n = 33) 0.649 ± 0.084 (n = 33)
BONEMARKERS     
OC (ng/ml) 9.74 ± 3.16 (n = 31) 10.17 ± 3.91 (n = 27) 10.65 ± 3.32 (n = 27) 10.16 ± 3.67 (n = 25)
BAP (U/L) 21.65 ± 6.30 (n = 32) 20.43 ± 7.24 (n = 26) 21.85 ± 6.31 (n = 27) 21.58 ± 7.36 (n = 27)
PINP (μg/L) 47.20 ± 13.45 (n = 30) 46.28 ± 21.46 (n = 26) 44.78 ± 16.07 (n = 28) 48.77 ± 15.09 (n = 30)
DPD (/Cr) 5.57 ± 3.12 (n = 28) 5.22 ± 1.50 (n = 26) 5.74 ± 1.45 (n = 27) 5.92 ± 1.57a (n = 28)
CTX-I (μg/mmol Cr) 359.01 ± 129.89 (n = 31) 331.88 ± 155.87 (n = 26) 349.10 ± 126.71 (n = 27) 360.43 ± 139.00 (n = 28)
  1. Baseline characteristics of patients (n = 136), mean ± SD, a: p < 0.05 (unpaired t-test) versus placebo, b: p < 0.05 (unpaired t-test) versus 3 mg Si.