Figure 2
From: Tibolone inhibits bone resorption without secondary positive effects on cartilage degradation
Cartilage degradation: Upper panel: Urinary CTXII (lower panel) during 2 years of therapy in the groups receiving 2.5 mg, 1.25 mg of tibolone, or placebo. Values shown are geometric mean ± 1 SEM. Lower panel: Mean relative change from baseline in urinary CTXII during 2 years of therapy with 1.25 and 2.5 mg of tibolone. Values shown are placebo-corrected time-averaged mean change during the treatment period and given as mean ± 1 SEM. Levels did not reach significance.