Skip to main content

Table 5 Transcriptional profiles of growth factors present on equine cDNA microarray

From: Differential gene expression associated with postnatal equine articular cartilage maturation

Gene Name Gene Symbol Total Probe Sets Median Fold Difference (N/A) Probe sets with p < 0.01 Probe sets with p < 0.05
Bone morphogenetic protein 2 BMP2 6 0.99 0 1
Bone morphogenetic protein 4 BMP4 1 0.81 0 0
Bone morphogenetic protein 6 BMP6 1 0.79 0 0
Bone morphogenetic protein receptor 1a BMPR1A 1 0.91 0 0
Bone morphogenetic protein receptor 2 BMPR2 2 0.73 0 0
Connective tissue growth factor CTGF 1 0.82 0 0
Fibroblast growth factor 2 FGF2 2 0.76 0 2
Fibroblast growth factor 10 FGF10 1 0.35 0 1
Fibroblast growth factor 18 FGF18 1 1.03 0 0
Fibroblast growth factor receptor 1 FGFR1 2 0.97 0 0
Fibroblast growth factor receptor 2 FGFR2 3 0.59 0 2
Fibroblast growth factor receptor 3 FGFR3 2 0.74 0 2
Fibroblast growth factor receptor-like 1 FGFRL1 4 0.84 1 2
Growth differentiation factor 5 GDF5 1 0.90 1 1
Growth differentiation factor 6 GDF6 1 1.07 1 1
Growth differentiation factor 10 GDF10 2 0.74 0 1
Insulin-like growth factor 1 IGF1 1 0.89 0 1
Insulin-like growth factor receptor 1 IGFR1 2 0.86 0 0
Insulin-like growth factor 2 receptor IGF2R 1 1.12 0 1
Insulin-like growth factor binding protein 4 IGFBP4 1 0.83 0 0
Insulin-like growth factor binding protein 5 IGFBP5 3 1.05 1 1
Insulin-like growth factor binding protein 6 IGFBP6 1 0.78 0 0
Insulin-like growth factor binding protein 7 IGFBP7 3 0.85 0 1
Transforming growth factor β1 TGFβ1 2 1.11 0 0
Transforming growth factor β1-like 1 TGFβ1L1 2 0.98 0 0
Transforming growth factor β2 TGFβ2 5 0.96 0 1
Transforming growth factor β3 TGFβ3 2 0.86 0 0
Transforming growth factor β receptor 1 TGFβR1 1 0.73 0 0
Transforming growth factor β receptor 2 TGFβR2 1 0.70 0 0
Transforming growth factor β receptor 3 TGFβR3 5 0.45 3 5
Transforming growth factor β receptor associated protein 1 TGFβRAP1 1 0.91 0 0
  1. Gene Name & Gene Symbol: gene identity of best BLAST match homologue to cDNA or plasmid; Total probe sets: Number of probe sets on the microarray representing the gene based on best BLAST match results; Median Fold Difference (N/A): Relative median Neonate/Adult fold change (bold represents fold difference > 2); Probe sets with p < 0.01 or 0.05: number of probe sets for each gene meeting these criteria by one-sample t-test.