The association between C-reactive protein and the likelihood of progression to joint replacement in people with rheumatoid arthritis: a retrospective observational study

Table 3 Cox proportional hazards model for first total joint replacement after one-year CRP observation (n = 1,230; 4.2% events)

Variables in the Equation	B	SE	p	HR	95% CI for HR
					Lower	Upper
Age at index	0.061	0.012	0.000	1.06	1.04	1.09
1-year CRP change (cf. Low-Low)			0.203
Low to High	0.623	0.504	0.217	1.86	0.69	5.01
High to Low	0.375	0.487	0.441	1.46	0.56	3.78
High-High	0.786	0.382	0.040	2.19	1.04	4.64

Covariates not reaching threshold significance: gender; time to 1st CRP observation.
Low CRP defined as ≤ 10 mmol/L; High CRP defined as >10 mmol/L

ISSN: 1471-2474