Skip to main content

Table 1 The numbers of myofibers co-expressing fast type, slow type, and/or developmental MHCs in skeletal muscles of a normal (10 months old) or a CXMDJ dog (11 months old).

From: Dystrophin deficiency in canine X-linked muscular dystrophy in Japan (CXMDJ) alters myosin heavy chain expression profiles in the diaphragm more markedly than in the tibialis cranialis muscle

  TC Diaphragm
  Normal Affected Normal Affected
Developmental - - + - - +
Fast 265 (73%) 85 (40%) 155 (70%) 222 (48%) 12 (1%) 20 (3.6%)
Fast & slow 0 (0%) 38 (18%) 67 (30%) 0 (0%) 160 (16%) 370 (66.8%)
Slow 96 (27%) 88 (42%) 1 (0%) 243 (52%) 847 (83%) 164 (29.6%)
Total 361 (100%) 211 (49%) 223 (51%) 465 (100%) 1019 (65%) 554 (35%)
  1. The numbers of fibers analyzed were results from a normal or an affected dog. MHC expression between two groups (normal, dMHC (-) vs affected, dMHC (-); affected, dMHC (-) vs affected, dMHC (+)), or between muscles (TC muscle vs diaphragm) was analyzed by Yates's chi-square test. Significant differences (p < 0.05) were detected in all tests.