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Table 1 Clinical, pathological and radiographic data

From: Rare clinical experiences for surgical treatment of melanoma with osseous metastases in Taiwan

Patient age (years)

Sex

Primary tumor

Clinical size (cm)

Microscopic classification

Depth (Clark level)

Osseous metastases and complications

Radiographic manifestation

Other metastases

Synchronous tumor

45

F

Scalp

1.5 × 1.0

Malignant melanoma

V

Frontoparietal skull, multiple cervico- thoracolumbar spine (compression fractures of thoracolumbar spine), bone marrow infiltration

Multiple spinal metastases with bony destruction and cord compression

Liver, bone marrow

None

72

M

L anterior chest wall

1.5 × 1.5

Malignant melanoma

IV

5th lumbar vertebra, R acetabulum

L5 compression fracture with bony destruction

Lung, Lymph nodes

None

64

M

R sole

1.5 × 1.5

acral lentiginous melanoma

V

L skull base, midcervical, mid thoracolumbar spine

Multiple bony destruction, permeative osteolytic skull lesion

Lung

None

79

M

L sole

1.0 × 1.0

acral lentiginous melanoma

III

R scapular, thoracolumbar spine (L2 compression fracture), L sacroiliac joint, pelvic rim and bilateral femurs

Multiple bony destruction with periosteal reaction and dystrophic calcifications

Lymph nodes

Lung cancer

62

M

L sole

2.3 × 2.1

acral lentiginous melanoma

IV

L ninth rib, thoracolumbar spine

Sclerotic lesions in thoracolumbar spine

Liver

Thyroid papillary carcinoma, renal cell carcinoma

67

F

R heel

3.5 × 1.0

acral lentiginous melanoma

V

R femoral pathological fracture, R knee, L mid femur, R scapular, rib

Permeative osteolytic change

Lymph node, lung, liver

None

70

F

L lower leg

1.0 × 1.0

Malignant melanoma

IV

L femoral subtrochanteric fracture

Osteolytic bony destruction

Liver, spleen

Renal cell carcinoma

67

M

R foot

7.0 × 6.0

acral lentiginous melanoma

V

R tibia, proximal femur

Increased tracer uptake over R proximal femur

Lung, lymph nodes

None

39

F

L subungual

1.1 × 0.9

acral lentiginous melanoma

V

Skull, thoracolumbar spine, thoracic cage, pelvic rim

Osteolytic bony destruction

Liver, lung, lymph nodes, brain

None

74

F

L lower limb

1.0 × 0.8

Malignant melanoma

V

L midtibial pathological fracture, sacroiliac joint

Osteolytic bony destruction

Lung

Cervical cancer

51

M

Unknown

NA

Malignant melanoma

NA

R navicular pathological fracture

Comminuted fracture

Liver, lung, lymph nodes

None

  1. L, left; R, right; NA, not applicable.