From: Rare clinical experiences for surgical treatment of melanoma with osseous metastases in Taiwan
Patient age (years) | Sex | Primary tumor | Clinical size (cm) | Microscopic classification | Depth (Clark level) | Osseous metastases and complications | Radiographic manifestation | Other metastases | Synchronous tumor |
---|---|---|---|---|---|---|---|---|---|
45 | F | Scalp | 1.5 × 1.0 | Malignant melanoma | V | Frontoparietal skull, multiple cervico- thoracolumbar spine (compression fractures of thoracolumbar spine), bone marrow infiltration | Multiple spinal metastases with bony destruction and cord compression | Liver, bone marrow | None |
72 | M | L anterior chest wall | 1.5 × 1.5 | Malignant melanoma | IV | 5th lumbar vertebra, R acetabulum | L5 compression fracture with bony destruction | Lung, Lymph nodes | None |
64 | M | R sole | 1.5 × 1.5 | acral lentiginous melanoma | V | L skull base, midcervical, mid thoracolumbar spine | Multiple bony destruction, permeative osteolytic skull lesion | Lung | None |
79 | M | L sole | 1.0 × 1.0 | acral lentiginous melanoma | III | R scapular, thoracolumbar spine (L2 compression fracture), L sacroiliac joint, pelvic rim and bilateral femurs | Multiple bony destruction with periosteal reaction and dystrophic calcifications | Lymph nodes | Lung cancer |
62 | M | L sole | 2.3 × 2.1 | acral lentiginous melanoma | IV | L ninth rib, thoracolumbar spine | Sclerotic lesions in thoracolumbar spine | Liver | Thyroid papillary carcinoma, renal cell carcinoma |
67 | F | R heel | 3.5 × 1.0 | acral lentiginous melanoma | V | R femoral pathological fracture, R knee, L mid femur, R scapular, rib | Permeative osteolytic change | Lymph node, lung, liver | None |
70 | F | L lower leg | 1.0 × 1.0 | Malignant melanoma | IV | L femoral subtrochanteric fracture | Osteolytic bony destruction | Liver, spleen | Renal cell carcinoma |
67 | M | R foot | 7.0 × 6.0 | acral lentiginous melanoma | V | R tibia, proximal femur | Increased tracer uptake over R proximal femur | Lung, lymph nodes | None |
39 | F | L subungual | 1.1 × 0.9 | acral lentiginous melanoma | V | Skull, thoracolumbar spine, thoracic cage, pelvic rim | Osteolytic bony destruction | Liver, lung, lymph nodes, brain | None |
74 | F | L lower limb | 1.0 × 0.8 | Malignant melanoma | V | L midtibial pathological fracture, sacroiliac joint | Osteolytic bony destruction | Lung | Cervical cancer |
51 | M | Unknown | NA | Malignant melanoma | NA | R navicular pathological fracture | Comminuted fracture | Liver, lung, lymph nodes | None |