Figure 1
Film in situ zymography (FIZ-GN) of skeletal muscle in CXMD J dogs. Hematoxylin and eosin (H&E) staining (A, C, D, and F) and film in situ zymography (FIZ-GN) (B, E, and G) of the tibialis cranialis muscle in a normal dog (A, B) and a CXMDJ dog (C-G). D and E (magnified views of C-a): a representative area of massive necrotic fibers with inflammatory infiltrate. F and G (magnified views of C-b): a representative area of a group of regenerating fibers. Gelatinolytic activities were visualized as white or weakly red areas on the red background. Bars, 100 μm.