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Table 1 Developmental genes undergoing up-regulation following exposure to dexamethasone

From: Gene expression analysis in human osteoblasts exposed to dexamethasone identifies altered developmental pathways as putative drivers of osteoporosis

Accession Gene SLR 30 SLR 60 SLR 120 SLR 240
N25732 FOXO3A -0.1 0.4 0.9 1.6
NM_012242.1 DKK1 0.1 0.5 0.9 1.6
NM_002015.2 FOXO1A -0.1 0.0 0.7 1.1
NM_005842.1 SPRY2 0.3 1.6 1.1 0.9
AI572079 SNAI2 0.3 0.7 1.1 0.8
NM_003243.1 TGFBR3 0.1 0.0 -0.3 0.7
NM_030775.1 WNT5B 0.0 0.2 0.2 0.7
NM_016932.1 SIX2 0.3 0.2 0.0 0.6
BC004395.1 APOL2 0.1 0.0 0.1 0.6
NM_001554.1 CYR61 0.4 0.4 0.1 0.5
NM_005359.1 MADH4 0.6 0.1 0.1 0.5
U52914.1 LEPR 0.3 0.1 -0.2 0.5
AI951720 TLE1 -0.1 0.1 0.2 0.5
AF308601.1 NOTCH2 0.2 0.0 -0.1 0.5
M24782.1 ELN -0.1 -0.1 0.0 0.5
M60721.1 HLX1 0.0 0.1 0.2 0.5
NM_003062.1 SLIT3 0.2 0.0 0.0 0.5
NM_001430.1 EPAS1 0.2 0.1 0.0 0.5
NM_001423.1 EMP1 0.2 0.1 0.6 0.5
NM_004335.2 BST2 0.2 0.1 0.4 0.4
NM_003244.1 TGIF 0.3 0.1 0.4 0.4
AF072872.1 FZD1 0.3 0.2 0.2 0.4
AI264196 FBN1 0.2 -0.2 -0.3 0.4
AI962897 SEMA3C 0.5 -0.1 -0.3 0.4
NM_001448.1 GPC4 0.3 -0.1 0.2 0.4
AF281859.1 SHFM3 0.3 0.2 0.3 0.4
NM_000041.1 APOE 0.1 0.3 0.3 0.4
NM_016453.1 AF3P21 0.2 0.2 0.2 0.4
NM_006884.1 SHOX2 -0.1 0.0 -0.2 0.4
NM_004472.1 FOXD1 0.2 0.4 0.0 0.3
NM_005251.1 FOXC2 -0.1 0.4 0.1 0.3
NM_012062.1 DNM1L 0.4 0.0 0.0 0.3
AI812030 THBS1 0.2 0.0 -0.4 0.3
NM_001992.2 F2R 0.1 -0.6 0.2 0.2
NM_003483.2 HMGA2 0.0 0.0 0.6 0.2
H71805 MCL1 -0.1 0.8 0.6 0.1
AW190873 ROD1 0.0 -0.2 -0.5 0.1
NM_013246.1 CLC -0.1 0.4 -0.1 0.1
NM_005882.2 MAEA 0.4 0.0 -0.2 0.1
  1. (SLI of ≥ 5 and a SLR ≤ -0.4 and ≥ +0.4 in one or more timepoints compared to control (T1)
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