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Table 2 Baseline characteristics of 24 patients included in the study.

From: Growth hormone as concomitant treatment in severe fibromyalgia associated with low IGF-1 serum levels. A pilot study

Data, mean (SD)

r-hGH

(n = 12)

Control

(n = 12)

p value

t student test

Demographics

   

   Age, years

47,4 (7,6)

49,6 (9,4)

0.555

   Weight, kg

72,9 (12,3)

66,0 (9,4)

0.153

   Waist, cm

89.2 (10.3)

76.6 (3.2)

0.01

   BMI, Kg/m2

25,1 (5,3)

162,2 (5,9)

0.334

Fibromyalgia symptoms duration (prior study), months

21 (6)

23 (7)

0,204

Vital signs

   

   Systolic blood pressure, mm Hg

124,8 (15,4)

117,5 (10,3)

0.222

   Diastolic blood pressure, mm Hg

80,8 (6,6)

74,2 (7,9)

0.052

   Heart rate, beats/min

75,8 (6,4)

77,9 (11,8)

0.721

Laboratory data

   

   GH, ng/mL

0,4 (0,3)

0,9 (0,8)

0.134

   IGF-1 g/L

173.3 (49.4)

98.6 (36.0)

<0.001

   TSH, μU/mL

1.3 (0.9)

1.3 (0.9)

0.998

   free T4, ng/mL

3.3 (4.9)

5.5 (6.9)

0.433

   free T3, pg/mL

3.7 (0.7)

2.9 (0.5)

0.041

   Estradiol E2, pg/mL

117.8 (17.7)

98.4 (81.7)

0.708

   P4, ng/mL

0.4 (0.3)

0.7 (0.3)

0.287

   Urinary free cortisol, μg/24 h

98.2 (66.1)

44.5 (11.9)

0.030

   Insulinemia U/dL

11.9 (14.7)

6.0 (2.7)

0.306

   Apolipoprotein B, mg/L

102.8 (26.7)

98.7 (66.1)

0.744

   C-Reactive protein, mg/L

3.2 (0.4)

3.5 (0.0)

0.417

   Erythrocyte sedimentation rate, mm

12.8 (5.8)

11.0 (4.6)

0.482