A systematic review of outcomes assessed in randomized controlled trials of surgical interventions for carpal tunnel syndrome using the International Classification of Functioning, Disability and Health (ICF) as a reference tool

Table 1 Summary of randomized controlled trials of surgical interventions for carpal tunnel syndrome

First Author/date	Country	Experimental intervention	Control	Sample size		Length of follow-up (weeks)
				Patients	hands
Holmgren-Larsson (1985)	Sweden	OCTR with epineurotomy.	OCTR	48	48	36
Lowry (1988)	USA	OCTR with neurolysis	OCTR	41	50	12
Mackinnon l (1991)	Canada	OCTR with neurolysis	OCTR	59	64	52
Agee (1992)	USA	ECTR	OCTR	122	147	26
Brown (1993)	USA	ECTR	OCTR	145	169	12
Erdmann (1994)	UK	ECTR	OCTR	71	105	52
Foulkes (1994)	USA	OCTR with epineurotomy	OCTR	33	36	52
Sennwald (1995)	Switzerland	ECTR	OCTR	47	47	12
Dumontier (1995)	France	ECTR	OCTR	96	96	36
Jacobsen (1996)	Sweden	ECTR	OCTR	29	32	36
Leinberry (1997)	USA	OCTR with epineurotomy	OCTR	44	50	52
Citron (1997)	UK	OCTR (L-incision)	OCTR	47	47	52
Nakamichi (1997)	Japan	OCTR with Ultrasound	OCTR	103	103	104
Brüser (1999)	Germany	OCTR (short incision.)	OCTR	80	80	6
Mackenzie (2000)	USA	ECTR	OCTR	26	36	4
Trumble (2002)	USA	ECTR	OCTR	147	192	52
Jugovac (2002)	Croatia	OCTR (short incision)	OCTR	72	72	12
Shum (2002)	USA	OCTR with Flexor tenosyn	OCTR	87	88	52
Ferdinand (2002)	UK	ECTR	OCTR	25	50	52
Borisch (2003)	Germany	OCTR with epineurotomy	OCTR	273	307	52
Macdermid (2003)	Canada	ECTR	OCTR	123	123	52
Saw (2003)	UK	ECTR	OCTR	123	123	12
Helm (2003)	UK	'Knifelight' ECTR	OCTR	82	82	6
Wong (2003)	China	'limited' OCTR	ECTR	30	60	52
Battacharya (2004)	UK	Knifelight' ECTR	OCTR	26	52	6
Dias (2004)	UK	Lengthening of flex ret.	OCTR	26	52	25
Kharwadkar (2005)	UK	OCTR absorbable sutures	OCTR	33	40	12
Lorgelly (2005)	UK	Minimally invasive OCTR	OCTR	194	208	104
TOTAL n = 28				2232	2558

ECTR = endoscopic carpal tunnel release; OCTR = Open carpal tunnel release; flex ret. = flexor retinaculum; tenosyn = tenosynovectomy

ISSN: 1471-2474