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Table 4 Summary of effectiveness

From: Nonsteroidal anti-inflammatory drugs (NSAIDs), cyxlooxygenase-2 selective inhibitors (coxibs) and gastrointestinal harm: review of clinical trials and clinical practice

Strategy

Efficacy

Appropriate prescribing

Adherence

Upper gastrointestinal injury

Coxib

Extensive, robust evidence

Low

Effective

NSAID + PPI

Surrogate only

Low

Low adherence

NSAID + H2A

Surrogate only

Low

Low adherence

Lower gastrointestinal injury

Coxib

Some evidence of efficacy

Low

Effective

NSAID + PPI

Some evidence of lack of efficacy

Low

Low adherence

NSAID + H2A

No evidence

Low

Low adherence

  1. Summarised from Hooper et al, 2004 [24].