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Table 1 Bone volume in the remodelled area and ingrowth distance of new bone into the graft. Bone volume fraction in the remodelled bone measured with Merz grid and expressed in percent of total tissue volume. Bone and vasculature ingrowth distance from living tissue into the graft.

From: Systemic zoledronate treatment both prevents resorption of allograft bone and increases the retention of new formed bone during revascularization and remodelling. A bone chamber study in rats

 

Zoledronat

Control

p

 

Mean

SD

Mean

SD

 

New-formed bone (%)

22

7

14

9

0.03

Remaining graft bone (%)

13

6

5

5

0.008

Total Bone (%)

35

0.12

19

0.13

0.01

Bone ingrowth distance into graft (mm)

2,65

0.48

2,12

0.63

0.052 ns

Vasculature ingrowth distance (mm)

4.2

0.90

3.90

1.01

Ns