Table 3 Distribution of COMT genotypes (Met/Met and pooled Met/Val or Val/Val) in controls and different chronic MSCs groups separated by gender
Men | Women | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Met/Met | Met/Val or Val/Val | p | Met/Met | Met/Val or Val/Val | p | |||||
Genotypes | ||||||||||
Controls (%) | 259 | 34.7 | 487 | 65.3 | 246 | 33.2 | 496 | 66.8 | ||
Chronic MSCs (%) | 185 | 29.4 | 444 | 70.6 | 0.04 | 272 | 30.2 | 628 | 69.8 | 0.22 |
Chronic neck pain (%) | 58 | 26.5 | 161 | 73.5 | 0.03 | 91 | 29.3 | 220 | 70.7 | 0.25 |
Chronic shoulder pain (%) | 72 | 28.3 | 182 | 71.7 | 0.07 | 109 | 31.4 | 238 | 68.6 | 0.62 |
Chronic elbow pain (%) | 20 | 22.7 | 68 | 77.3 | 0.03 | 52 | 32.1 | 110 | 67.9 | 0.87 |
Chronic wrist/hand pain (%) | 36 | 27.9 | 93 | 72.1 | 0.16 | 68 | 28.9 | 167 | 71.1 | 0.26 |
Chronic chest/abdomen pain (%) | 17 | 28.3 | 43 | 71.7 | 0.39 | 37 | 35.9 | 66 | 64.1 | 0.66 |
Chronic upper back pain (%) | 30 | 37.5 | 50 | 62.5 | 0.71 | 63 | 33.7 | 124 | 66.3 | 0.96 |
Chronic lower back pain (%) | 67 | 30.7 | 151 | 69.3 | 0.31 | 87 | 28.2 | 221 | 71.8 | 0.14 |
Chronic hip pain (%) | 44 | 28.0 | 113 | 72.0 | 0.13 | 94 | 32.1 | 199 | 67.9 | 0.80 |
Chronic knee pain (%) | 46 | 28.4 | 116 | 71.6 | 0.15 | 91 | 30.3 | 209 | 69.7 | 0.42 |
Chronic ankle/foot pain (%) | 40 | 29.0 | 98 | 71.0 | 0.23 | 75 | 28.8 | 185 | 71.2 | 0.23 |
Chronic widespread pain (%) | 60 | 30.0 | 140 | 70.0 | 0.24 | 102 | 30.7 | 230 | 69.3 | 0.47 |