Influences of obese (ob/ob) and diabetes (db/db) genotype mutations on lumber vertebral radiological and morphometric indices: Skeletal deformation associated with dysregulated systemic glucometabolism

Table 3 Influences of E2-HRx on body weights and blood glucose levels in control and diabetes-mutant C57BL/KsJ mice

Group	Age (weeks)	HRx	Parameters
			Body Weight(g)	Blood Glucose(mg/dl)
Control	8	Oil	21.1 ± 0.3	109 ± 8
		E2	21.8 ± 2	118 ± 8
Diabetes	8	Oil	33.7 ± 0.8*	278.5 ± 23*
		E2	34.2 ± 0.7*	261.1 ± 16*
Control	16	Oil	25.2 ± 0.5	128.3 ± 8
		E2	24.2 ± 0.5	113.3 ± 9
Diabetes	16	Oil	41.0 ± 3.4*	356.6 ± 38*
		E2	44.1 ± 1.8*	138.3 ± 20^#

Comparisons between indicated phenotype and systemic endocrine/metabolic parameters in control, diabetes- or obese-mutant C57BK/KsJ mice at 8 and 16 weeks of age are demoted as group means (± SEM) for the designated number (N) of animals per group. Significant (P ≤ 0.05) intergroup differences (i.e. control v.s. genotype group values) at the designated age are indicated by asterisks (*).

ISSN: 1471-2474