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Figure 5 | BMC Musculoskeletal Disorders

Figure 5

From: Analyses of the differentiation potential of satellite cells from myoD -/-, mdx, and PMP22 C22 mice

Figure 5

IGF-1 treatment fails to rescue differentiation of satellite cells in culture. Satellite cells from control or mdx animals at the age of 6 months were treated with IGF-1 (100 ng/ml medium) during either proliferation (P+IGF), differentiation (D+IGF), both (P+IGF D+IGF), or neither (P+D+, control). A. Differentiation was unaltered by IGF-1 addition. B. Non-myogenic cells are more abundant in mdx than control single fibre cultures.

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