Figure 3
From: Analyses of the differentiation potential of satellite cells from myoD -/-, mdx, and PMP22 C22 mice
Differentiation of satellite cells of control and mdx mice of different ages in vitro. A. Box and whisker plot: The box extends from the 25th percentile to the 75th percentile between all animals of one age, with a horizontal line at the median (50th percentile). Whiskers show the range of the data. B. Mean differentiation for each individual animal shows heterogeneity between mdx animals. Individuals showing poor differentiation (8 in total) are significantly more common in mdx (X2, P = 0.0076). C. Satellite cell cultures from single fibres of 12 month old control C57BL/10ScSn and mdx animals showing good differentiation in each case. Blue nuclei: DAPI; desmin: red, Cy3; MyHC: green, FITC in both genotypes.