Figure 2
From: Analyses of the differentiation potential of satellite cells from myoD -/-, mdx, and PMP22 C22 mice
Differentiation of satellite cells of the HMSN1A mouse model PMP22 C22 at three ages. A. Variation in soleus muscle cryosections reacted for slow MyHC reveals variable pathology of individual PMP22 C22 mice. Note fibre atrophy (arrowheads) and large, hypertrophied fibres in the middle compared to the right panel. B. Satellite cells from single fibre culture of PMP22 C22 and littermate controls were analysed for cell yield, proliferation and terminal differentiation. No significant differences were observed.