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Table 5 Total Costs of Care for RA Patients at One Year

From: Patterns of use, dosing, and economic impact of biologic agent use in patients with rheumatoid arthritis: a retrospective cohort study

 

Infliximab N = 598

Etanercept N = 950

Infliximab: Dose Escalation vs. No Escalation (p-value)

 

Dose Escalation

No Escalation

Dose Escalation

No Escalation

 
 

N = 346

N = 252

N = 172

N = 778

 

Measure

Cost per patient (mean, SE), $

 

RA Related Costs

$20,914.98 (631.15)

$16,713.20 (1,315.86)

$14,482.45 (519.97)

$13,865.48 (306.88)

<0.0001

   Pharmacy:

     

Infliximab

$15,997.65 (413.51)

$9,999.87 (293.82)

$313.88 (175.79)

$197.56 (53.23)

<0.0001

Etanercept

$101.26 (45.32)

$178.18 (63.03)

$10,426.90 (254.66)

$10,099.71 (124.94)

 

Other

$1,049.00 (69.20)

$1,045.57 (145.45)

$1,089.33 (88.71)

$1,009.24 (48.61)

 

Total Pharmacy

$17,147.90 (418.81)

$11,223.62 (350.97)

$11,830.12 (292.80)

$11,306.51 (136.87)

 

   Outpatient:

     

Management

$635.68 (53.29)

$766.75 (112.25)

$377.98 (29.58)

$382.19 (41.21)

 

Emergency Room

$13.85 (4.11)

$12.54 (6.32)

$4.72 (1.81)

$7.09 (1.76)

 

Ancillary

$1,601.47 (116.33)

$1,387.33 (118.42)

$842.11 (122.13)

$871.60 (90.63)

 

Total Outpatient

$2,251.00 (136.95)

$2,166.62 (176.82)

$1,224.81 (135.67)

$1,260.88 (120.64)

 

   Hospitalization Costs

$1,516.08 (393.06)

$3,322.95 (1,191.16)

$1,427.52 (411.72)

$1,298.08 (249.13)

 

Non-RA Related Costs

$5,370.17 (536.68)

$6,104.37 (1,210.40)

$3,954.81 (415.94)

$4,177.57 (281.46)

0.0302

Grand Total

$26,285.15 (1,022.19)

$22,817.56 (2,431.57)

$18,437.26 (809.69)

$18,043.04 (496.95)

<0.0001