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Table 1 Nerve-related genes up-regulated by fracture at all three ages

From: Altered mRNA expression of genes related to nerve cell activity in the fracture callus of older rats: A randomized, controlled, microarray study

GenBank Name Reference
Genes related to apoptosis
S67769 Cardiac sodium/calcium exchanger (Slc8a1) [38]
M82824 Leucopus neurofibromatosis protein – type 1 (NF1) [39]
L11319 Signal peptidase complex 18kD [40]
Genes up-regulated by injury
J03624 Galanin (shown in Fig. 2) [41–43]
E12625 Rat novel protein expressed with nerve injury (sterol-C4-methyl oxidase-like) [44]
Genes related to nerve cell differentiation and growth
Z11558 Glia maturation factor beta [45–47]
A03913 Glia-derived neurite-promoting factor (serine (or cysteine) proteinase inhibitor, clade E, member 2) [48,49]
E05646 Hippocampal cholinergic neurostimulating peptide (phosphatidylethanolamine binding protein) [50]
AB011531 MEGF 5, slit homolog 3 [51]
AA924772 Metallothionein 3 [52,53]
AF097593 N-cadherin, Testicular (cadherin 2) [54,55]
AF023087 Nerve growth factor induced factor A (early growth response 1) [56,57]
AI102795 Pleiotrophin (heparin binding growth factor 8, Hbnf, neurite growth promoting factor 1) (Fig. 2) [58–60]
L19180 Receptor-linked protein tyrosine phosphatase type D (protein tyrosine phosphatase, receptor type D) [61]
AF044910 Survival motor neuron [62]
U64689 Synaptotagmin interacting protein zygin II (fasciculation and elongation protein zeta 2) [63]
Other genes
L07281 Carboxypeptidase E [64,65]
U03416 Neuronal olfactomedin-related ER localized protein [66]
U67140 PSD-95/SAP 90 associated protein-4 (disks large-associated protein 4) [67]
M83680 RAB14 (GTPase Rab 14) [68]
AF016247 RTK40 homolog (tyro 10, discordin domain receptor family, member 2) [69]
X65454 SC65 – Synaptonemal complex protein [70]
AJ006855 Synaptojanin 1 [71]
M96601 Taurine transporter (Slc6a6) [72]
U35245 Vacuolar protein sorting homolog r-vps33b [73]
  1. Alternative names are shown in parentheses. References to physiological roles are shown to the right.