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Table 1 Nerve-related genes up-regulated by fracture at all three ages

From: Altered mRNA expression of genes related to nerve cell activity in the fracture callus of older rats: A randomized, controlled, microarray study

GenBank

Name

Reference

Genes related to apoptosis

S67769

Cardiac sodium/calcium exchanger (Slc8a1)

[38]

M82824

Leucopus neurofibromatosis protein – type 1 (NF1)

[39]

L11319

Signal peptidase complex 18kD

[40]

Genes up-regulated by injury

J03624

Galanin (shown in Fig. 2)

[41–43]

E12625

Rat novel protein expressed with nerve injury (sterol-C4-methyl oxidase-like)

[44]

Genes related to nerve cell differentiation and growth

Z11558

Glia maturation factor beta

[45–47]

A03913

Glia-derived neurite-promoting factor (serine (or cysteine) proteinase inhibitor, clade E, member 2)

[48,49]

E05646

Hippocampal cholinergic neurostimulating peptide (phosphatidylethanolamine binding protein)

[50]

AB011531

MEGF 5, slit homolog 3

[51]

AA924772

Metallothionein 3

[52,53]

AF097593

N-cadherin, Testicular (cadherin 2)

[54,55]

AF023087

Nerve growth factor induced factor A (early growth response 1)

[56,57]

AI102795

Pleiotrophin (heparin binding growth factor 8, Hbnf, neurite growth promoting factor 1) (Fig. 2)

[58–60]

L19180

Receptor-linked protein tyrosine phosphatase type D (protein tyrosine phosphatase, receptor type D)

[61]

AF044910

Survival motor neuron

[62]

U64689

Synaptotagmin interacting protein zygin II (fasciculation and elongation protein zeta 2)

[63]

Other genes

L07281

Carboxypeptidase E

[64,65]

U03416

Neuronal olfactomedin-related ER localized protein

[66]

U67140

PSD-95/SAP 90 associated protein-4 (disks large-associated protein 4)

[67]

M83680

RAB14 (GTPase Rab 14)

[68]

AF016247

RTK40 homolog (tyro 10, discordin domain receptor family, member 2)

[69]

X65454

SC65 – Synaptonemal complex protein

[70]

AJ006855

Synaptojanin 1

[71]

M96601

Taurine transporter (Slc6a6)

[72]

U35245

Vacuolar protein sorting homolog r-vps33b

[73]

  1. Alternative names are shown in parentheses. References to physiological roles are shown to the right.