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Table 2 Biochemical assessment of sulfur amino acid status, mineral metabolism, and bone formation.

From: Chemical and biomechanical characterization of hyperhomocysteinemic bone disease in an animal model

Analyte

Group

 

Control

Experimental

Homocysteine (μmol/L)

43.8 ± 5.0

358 ± 58 ****

Methionine (μmol/L)

141 ± 9

175 ± 13 ***

Cystathionine (μmol/L)

39.8 ± 9.1

226 ± 20 ****

Total inorganic sulfate (mmol/L)

2.18 ± 0.44

3.09 ± 0.09 ***

Glutathione (μmol/L)

1141 ± 55

1066 ± 75

Pyridoxal-5'-phosphate (nmol/L)

162 ± 29

136 ± 46

Bone-specific alkaline phosphatase (IU/L)

2069 ± 317

2135 ± 370

Osteocalcin (μg/L)

1.58 ± 0.38

1.83 ± 0.63

IGF-1 (μg/L)

16.9 ± 4.3

14.2 ± 3.4

Total calcium (mmol/L)

10.8 ± 0.2

10.7 ± 0.2

Phosphate (mmol/L)

7.3 ± 0.8

7.1 ± 0.9

  1. ****P < 0.0001 *** P < 0.001