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Table 3 Bone markers

From: Effect of simvastatin on bone markers in osteopenic women: a placebo-controlled, dose-ranging trial [ISRCTN85429598]

  Placebo Simvastatin 20 Simvastatin 40
  Baseline 6 weeks 12 weeks Baseline 6 weeks 12 weeks Baseline 6 weeks 12 weeks
NTX-I, nM BCE 15.5 ± 1.8 15.7 ± 2.0 15.9 ± 1.4 16.5 ± 1.7 15.9 ± 1.2 19.6 ± 1.8 19.3 ± 2.4 17.6 ± 2.1 18.1 ± 2.0
CTX-I, ng/ml 95.4 ± 5.9 86.4 ± 7.9 86.9 ± 11.5 90.3 ± 10.1 83.2 ± 12.1 107.2 ± 18.8 108.2 ± 11.3 94.2 ± 14.1 120.7 ± 12.2
Bone ALP, U/L 14.3 ± 2.4 14.0 ± 2.5 14.4 ± 2.9 19.0 ± 3.0 17.4 ± 2.8 17.2 ± 2.8 14.3 ± 2.2 13.4 ± 2.2 14.0 ± 2.2
  1. Mean + SE