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Table 1

From: Systemic alendronate prevents resorption of necrotic bone during revascularization. A bone chamber study in rats

 

total bone volume

host bone volume

graft bone volume

alendr, high dose

70% (sd 18)

37% (sd 15)

34% (sd 5)

contr, high dose

27% (sd 13)

19% (sd 9)

8% (sd 4)

 

(p = 0.0002)

(p = 0.005)

(p = 0.0002)

alendr, low dose

29% (sd 11)

24% (sd 9)

5% (sd 2)

contr, low dose

18% (sd 9)

15% (sd 8)

3% (sd 3)

 

(p = 0.049)

n.s.

(p = 0.037)

not implanted grafts (ref [7])

 

38% (sd 10)