|
Exp
|
Dose
|
Time
|
N.Oc/T.Ar (#/mm2)
|
N.Oc/B.Pm (#/mm)
|
N.ApOc/T.Ar (#/mm2)
|
|---|
| | | |
Vehicle
|
1,25-(OH)2D3
|
Vehicle
|
1,25-(OH)2D3
|
Vehicle
|
1,25-(OH)2D3
|
|---|
|
2
|
3 × 10 μg/kg
|
4 d
|
33.9 ± 5.0
|
66.4 ± 5.5*
|
3.9 ± 0.7
|
7.7 ± 1.0*
|
0
|
4.6 ± 1.3*
|
|
3
|
3 × 2 μg/kg
|
4 d
|
31.0 ± 1.7
|
56.3 ± 3.3*
|
3.5 ± 0.4
|
6.9 ± 0.4*
|
0.5 ± 0.3
|
3.1 ± 0.4*
|
| | |
6 d
|
35.0 ± 4.2
|
16.7 ± 0.6*
|
4.1 ± 0.5
|
3.3 ± 0.1*
|
0.7 ± 0.2
|
3.5 ± 0.3*
|
| | |
9 d
|
30.6 ± 7.3
|
33.9 ± 4.7
|
3.8 ± 0.8
|
3.9 ± 0.7
|
0.7 ± 0.2
|
0.7 ± 0.2
|
| | |
13 d
|
26.7 ± 2.4
|
46.9 ± 4.8*
|
2.9 ± 0.4
|
5.1 ± 0.3*
|
0.7 ± 0.2
|
1.2 ± 0.4
|
| | |
17 d
|
30.3 ± 5.0
|
44.0 ± 4.5
|
3.5 ± 0.3
|
4.6 ± 0.6
|
0.5 ± 0.2
|
1.0 ± 0.3
|
|
4
|
3 × 0.2 μg/kg
|
4 d
|
28.8 ± 1.9
|
27.3 ± 1.9
|
3.0 ± 0.2
|
2.7 ± 0.2
|
0.2 ± 0.2
|
0
|
| | |
6 d
|
28.2 ± 1.5
|
27.1 ± 2.6
|
3.0 ± 0.1
|
3.0 ± 0.2
|
0.2 ± 0.2
|
0
|
| | |
8 d
|
26.9 ± 2.8
|
29.2 ± 2.2
|
2.9 ± 0.2
|
3.2 ± 0.4
|
0
|
0.4 ± 0.2
|
| | |
10 d
|
29.4 ± 2.4
|
31.7 ± 2.3
|
3.7 ± 0.1
|
3.1 ± 0.3
|
0.2 ± 0.2
|
0.4 ± 0.2
|
| | |
12 d
|
31.5 ± 2.7
|
32.5 ± 3.3
|
3.3 ± 0.3
|
3.6 ± 0.3
|
0.2 ± 0.2
|
0.2 ± 0.2
|
| | |
14 d
|
30.6 ± 3.2
|
29.8 ± 2.7
|
3.5 ± 0.3
|
3.5 ± 0.3
|
0
|
0.2 ± 0.2
|
- All values are mean ± SE, *: P < 0.05
