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Table 1 Effect of 1,25-(OH)2D3 on the number of TRAP +ve and ED1 +ve Bone Marrow Cells

From: Recruitment, augmentation and apoptosis of rat osteoclasts in 1,25-(OH)2D3 response to short-term treatment with 1,25-dihydroxyvitamin D3 in vivo

Exp

Dose

Time

TRAP +ve BMC (#/mm2)

ED1 +ve BMC (#/mm2)

   

Vehicle

1,25-(OH)2D3

Vehicle

1,25-(OH)2D3

1

1 × 10 μg/kg

2 d

1.60 ± 0.41

16.37 ± 4.53*

1.66 ± 0.33

16.67 ± 5.09*

2

3 × 10 μg/kg

2 d

0.33 ± 0.16

0.44 ± 0.19

2.08 ± 0.45

4.58 ± 1.25*

3

3 × 2 μg/kg

4 d

0.74 ± 0.13

0.67 ± 0.24

0.83 ± 0.33

1.46 ± 0.60

  

6 d

0.63 ± 0.21

0.56 ± 0.19

1.25 ± 0.33

11.04 ± 4.00*

  

9 d

0.59 ± 0.27

0.59 ± 0.19

0.83 ± 0.30

1.36 ± 0.28

  

13 d

0.56 ± 0.24

0.59 ± 0.24

1.36 ± 0.28

2.50 ± 1.18

  

17 d

0.74 ± 0.19

0.78 ± 0.14

1.25 ± 0.33

2.92 ± 0.79*

  1. All values are means ± SE, *: P < 0.05.