|
Exp
|
Dose
|
Time
|
TRAP +ve BMC (#/mm2)
|
ED1 +ve BMC (#/mm2)
|
|---|
| | | |
Vehicle
|
1,25-(OH)2D3
|
Vehicle
|
1,25-(OH)2D3
|
|---|
|
1
|
1 × 10 μg/kg
|
2 d
|
1.60 ± 0.41
|
16.37 ± 4.53*
|
1.66 ± 0.33
|
16.67 ± 5.09*
|
|
2
|
3 × 10 μg/kg
|
2 d
|
0.33 ± 0.16
|
0.44 ± 0.19
|
2.08 ± 0.45
|
4.58 ± 1.25*
|
|
3
|
3 × 2 μg/kg
|
4 d
|
0.74 ± 0.13
|
0.67 ± 0.24
|
0.83 ± 0.33
|
1.46 ± 0.60
|
| | |
6 d
|
0.63 ± 0.21
|
0.56 ± 0.19
|
1.25 ± 0.33
|
11.04 ± 4.00*
|
| | |
9 d
|
0.59 ± 0.27
|
0.59 ± 0.19
|
0.83 ± 0.30
|
1.36 ± 0.28
|
| | |
13 d
|
0.56 ± 0.24
|
0.59 ± 0.24
|
1.36 ± 0.28
|
2.50 ± 1.18
|
| | |
17 d
|
0.74 ± 0.19
|
0.78 ± 0.14
|
1.25 ± 0.33
|
2.92 ± 0.79*
|
- All values are means ± SE, *: P < 0.05.
