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Table 2 Clinical manifestations at the latest follow-up

From: Comparison of orthopaedic manifestations of multiple epiphyseal dysplasia caused by MATN3 versus COMP mutations: a case control study

  MATN3 group COMP group p-value
No. of patients 37 22  
Follow-up (year) 3.7 ± 3.9* 6.6 ± 5.2*  
Hip pain 3 (8.1)** 6 (27.3)** 0.084+
Knee pain 7 (18.9)** 5 (22.7)** 0.748+
Ankle pain 2 (5.4)** 1 (4.5)** 0.887+
Back pain 1 (2.7)** 0 (0)** 0.445+
Gait abnormality 4 (10.8)** 8 (36.4)** 0.037+
Limitation of daily activity 4 (10.8)** 7 (31.8)** 0.075+
  1. *Mean ± standard deviation, **number of patients (percentile).
  2. +Fisher’s exact test.