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Table 5 Univariate and multivariate analysis for association of osteoarthritis (OA) progression [defined by joint space narrowing (JSN)] with serum ferritin (dichotomized at third quintile)

From: Age-dependent ferritin elevations and HFE C282Y mutation as risk factors for symptomatic knee osteoarthritis in males: a longitudinal cohort study

OA progression variable

Odds ratio*

Adjusted Odds ratio**

[95% CI; P value]

[95% CI; P value]

All ( N = 120)

  

JSN (mm)

  

≤ 0.5 (N = 82)

0.42

0.32**

> 0.5 (N = 38)

[CI: 0.15–1.023; P = 0.046]

[CI: 0.12–0.81; P = 0.0170]

Female ( N = 76)

  

JSN (mm)

  

≤ 0.5 (N = 53)

0.076

0.07***

> 0.5 (N = 23)

[CI: 0.001–0.55; P = 0.002

[CI: 0.009–0.63; P = 0.016]

Male ( N = 44)

  

JSN (mm)

  

≤ 0.5 (N = 29)

0.91

0.79***

> 0.5 (N = 15)

[CI: 0.21–4.06; P = 1.0]

[CI: 0.21–3.02; P = 0.74]

  1. *Univariate logistic regression
  2. **Multivariate logistic regression adjusted for body mass index (BMI), age, sex.
  3. ***Multivariate logistic regression adjusted for body mass index (BMI), age.
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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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