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Table 4 Univariate and multivariate analyses in the osteoarthritis (OA) population for relationship between serum ferritin level and demographical, clinical, and radiographic variables at entry

From: Age-dependent ferritin elevations and HFE C282Y mutation as risk factors for symptomatic knee osteoarthritis in males: a longitudinal cohort study

Variables: All OA (N = 120) Serum ferritin P value* Odds ratio Adjusted Odds ratio
(ng/ml), mean ± SD [95% CI; P value**] [95% CI; P value***]
Sex:     
  Female (N = 76) 37.79 ±33.3 0.0001 4.1 NA
  Male (N = 44) 65.3 ±45.0   [CI: 1.76–9.87; P = 0.0004]  
Age (years):     
  ≤74 (N = 105) 45.8 ±39.8 0.047 3.48 NA
  >74 (N = 15) 61.9 ±40.8   [CI: 0.99–14.01; P = 0.045]  
JSW (mm) baseline:     
  >4 (N = 80) 34.4 ±30.0 0.032 3.2 2.66
  ≤4 (N = 40) 54.6 ±42.9   [CI: 1.29–8.78; P = 0.006] [CI: 1.07–6.64; P = 0.035]
KL severity baseline:     
  KL2 (N = 18) 46.3 ±40.6 0.975 1.505 1.63
  KL3/4 (N = 72) 48.6 ±39.7   [0.459–5.459; P = 0.5943] [0.54–5.00; P = 0.3859]
  1. *t test on log ferritin.
  2. **Chi-square test on dichotomized ferritin levels at third quintile.
  3. ***Logistic regression with adjustment for body mass index (BMI), age, sex.
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