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Table 4 Univariate and multivariate analyses in the osteoarthritis (OA) population for relationship between serum ferritin level and demographical, clinical, and radiographic variables at entry

From: Age-dependent ferritin elevations and HFE C282Y mutation as risk factors for symptomatic knee osteoarthritis in males: a longitudinal cohort study

Variables: All OA (N = 120)

Serum ferritin

P value*

Odds ratio

Adjusted Odds ratio

(ng/ml), mean ± SD

[95% CI; P value**]

[95% CI; P value***]

Sex:

    

  Female (N = 76)

37.79 ±33.3

0.0001

4.1

NA

  Male (N = 44)

65.3 ±45.0

 

[CI: 1.76–9.87; P = 0.0004]

 

Age (years):

    

  ≤74 (N = 105)

45.8 ±39.8

0.047

3.48

NA

  >74 (N = 15)

61.9 ±40.8

 

[CI: 0.99–14.01; P = 0.045]

 

JSW (mm) baseline:

    

  >4 (N = 80)

34.4 ±30.0

0.032

3.2

2.66

  ≤4 (N = 40)

54.6 ±42.9

 

[CI: 1.29–8.78; P = 0.006]

[CI: 1.07–6.64; P = 0.035]

KL severity baseline:

    

  KL2 (N = 18)

46.3 ±40.6

0.975

1.505

1.63

  KL3/4 (N = 72)

48.6 ±39.7

 

[0.459–5.459; P = 0.5943]

[0.54–5.00; P = 0.3859]

  1. *t test on log ferritin.
  2. **Chi-square test on dichotomized ferritin levels at third quintile.
  3. ***Logistic regression with adjustment for body mass index (BMI), age, sex.