Skip to main content

Table 1 Comparisons of demographic and clinical characteristics of patients with osteoarthritis (OA) and healthy individuals (control) at baseline, and of ferritin levels at baseline and 18-month follow-up

From: Age-dependent ferritin elevations and HFE C282Y mutation as risk factors for symptomatic knee osteoarthritis in males: a longitudinal cohort study

Variables: All Subjects (N = 147) Control (N = 20) OA (N = 127) P Value*
Age (years), mean ± SD 56.1 ± 9.0 65.1 ± 10.0 0.00034**
Female gender, number (%) 9 (45%) 80 (63.0%) 0.1446***
Caucasian race, number (%) 11 (55%) 86 (67.7%) 0.5099***
Ethnicity:    
 Hispanic, number (%) 4 (20%) 14 (11.0%) 0.4405***
 Non-Hispanic, number (%) 16 (80%) 113 (89.0%)  
BMI (kg/m2), mean ± SD 26.6 ± 4.1 26.6 ± 3.6 0.9547**
Genotypes, number (%):    
 +/+ (wild type) 15 (75%) 95 (74.8%) 0.7962***
 H63D/+ 5 (25%) 18 (14.2%)  
 C282Y/+ 0 7 (5.5%)  
 H63D/H63D 0 2 (1.6%)  
 C282Y/H63D 0 2 (1.6%)  
 C282Y/C282Y 0 3 (2.4%)  
Ferritin (ng/ml), mean ± SD:    
 Baseline 37.1 ± 23.0 59.1 ±114.9 0.3344**
 18-month follow-up 47.7 ± 34.5 53.3 ± 55.8 0.7747**
 Delta 8.8 ± 24.8 -6.6 ± 88.8 0.3317**
Variables: Male Subjects ( N= 58) Control ( N= 11) OA ( N= 47) P Value*
Age (years), mean ± SD 58.4 ± 10.1 67.1 ± 9.7 0.0205**
Caucasian race, number (%) 6 (54.5%) 34 (72.3%) 0.2901
Ethnicity:    
 Hispanic, number (%) 2 (18.2%) 14 (8.5%) 0.3178
BMI (kg/m2), mean ± SD 27.7 ± 3.5 26.6 ± 3.1 0.3716
  1. *P, comparison between OA group and healthy controls by **two-sample t-test or ***Chi-square test.
\