Skip to main content

Table 5 Pooled estimates of SMCs (95% confidence interval) for pain intensity for included RCTs and observational cohort studies

From: The clinical course of low back pain: a meta-analysis comparing outcomes in randomised clinical trials (RCTs) and observational studies

 

Pooled SMCs (95% CI)

 

6 weeks

13 weeks

27 weeks

52 weeks

 

n†

 

I 2

†

 

I 2

n†

 

I 2

n†

 

I 2

Cohorts

6

1.2 (0.7, 1.7)

99

9

1.0 (0.8, 1.3)

99

9

1.2 (0.8, 1.7)

99

11

1.1 (0.8, 1.6)

99

RCTs

60

1.0 (0.9, 1.0)

99

94

1.2 (1.1, 1.3)

100

101

1.1 (1.0, 1.2)

100

78

0.9 (0.8, 1.0)

99

p-value*

 

0.651

  

0.735

  

0.878

  

0.721

 

Efficacy RCTs

15

1.0 (0.9, 1.1)

99

13

1.2 (1.0, 1.4)

100

16

0.9 (0.7, 1.2)

100

14

0.7 (0.5, 0.8)

100

p-value**

 

0.663

  

0.549

  

0.574

  

0.104

 

Pragmatic RCTs

43

1.0 (0.9, 1.1)

99

81

1.2 (1.1, 1.4)

100

81

1.2 (1.0,1.3)

100

64

0.9 (0.8, 1.1)

100

p-value***

 

0.628

  

0.466

  

0.899

  

0.642

 

Usual Care RCT arms

   

8

1.2 (1.0, 1.3)

99

7

1.3 (1.7, 1.4)

99

7

1.0 (0.8, 1.2)

99

  1. †Number of cohort studies and RCTs treatment arms. *Meta-regression comparison between cohort studies and RCTs. efficacy RCTs, **Meta-regression comparison between cohort studies and efficacy RCTs. ***Meta-regression comparison between cohort studies and pragmatic RCTs.
Back to article page

BMC Musculoskeletal Disorders

ISSN: 1471-2474

Contact us