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Figure 4 | BMC Musculoskeletal Disorders

Figure 4

From: Twins discordant for myositis and systemic lupus erythematosus show markedly enriched autoantibodies in the affected twin supporting environmental influences in pathogenesis

Figure 4

Heatmap analysis of autoantibody seropositive twins. Heatmap analysis shows autoantibody seropositivity against the 15 autoantigens that were found in at least one of the twin pairs. Relative immunoreactivity against target autoantigens are shown for the 13 affected twins (panel A) and in 3 unaffected twins (panel B). As described in Materials and Methods, each twin pair was color-coded reflecting the relative-fold elevation in autoantibody levels among seropositive twins compared to their seronegative counterparts.

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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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