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Figure 2 | BMC Musculoskeletal Disorders

Figure 2

From: Twins discordant for myositis and systemic lupus erythematosus show markedly enriched autoantibodies in the affected twin supporting environmental influences in pathogenesis

Figure 2

Autoantibodies against additional autoantigen targets in the twin cohort. Samples from 93 subjects were evaluated for autoantibodies against (A.) Sm, (B.) La, (C.) Ku and (D.) PML antigens. The individual autoantibody levels are plotted on the Y-axis using a log10 scale and the median antibody value in each group is shown by the horizontal line. While a pre-determined cut-off along was seropositive status was assigned for La and Smith before the sample ID codes were revealed, the cut-off shown for the newly developed PML and Ku autoantigens were based on differences greater than the mean plus 3 standard deviations.

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