Typology of patients with fibromyalgia: cluster analysis of duloxetine study patients

Table 1 Mean scores and percent of patients meeting sds remission criterion by cluster at 12 weeks

		Mean score
Variable	Scale	Cluster 1 (worst),	Cluster 2 (physically poor),	Cluster 3 (mentally poor),	Cluster 4 (moderate),	Cluster 5 (best),
		N = 78	N = 135	N = 104	N = 185	N = 129
Pain
BPI - Average pain intensity	BPIAVP	7.58	5.93	4.12	3.55	1.43
BPI - Pain interference (overall score)	BPIPIF	7.89	4.77	4.21	2.23	0.60
FIQ item 15: Pain	FIQ15	8.71	7.03	5.03	4.42	1.70
Mental impairment
FIQ item 19: Anxiety	FIQ19	7.38	2.30	5.09	1.70	0.67
FIQ item 20: Depression	FIQ20	6.91	1.45	5.09	1.12	0.57
BDI total score	BDI	25.08	7.93	15.81	5.99	3.46
SF-36 mental composite summary score	SF36M	34.46	53.70	37.31	54.08	56.37
Physical impairment
FIQ - Physical impairment	FIQPI	6.77	4.42	4.55	2.56	1.23
FIQ item 14: Interference with work	FIQ14	8.26	6.29	4.82	3.16	0.77
FIQ item 16: Tiredness	FIQ16	9.18	7.82	7.31	5.88	2.28
FIQ item 17: Awoke rested	FIQ17	9.19	7.66	7.08	5.66	2.46
FIQ item 18: Stiffness	FIQ18	8.79	6.87	5.69	4.58	1.88
SF-36 physical composite summary score	SF36P	24.88	24.51	32.77	34.13	45.90
Global impression
CGI-S	CGIS	4.35	3.80	3.50	3.01	2.18
PGI-I	PGII	4.27	3.61	2.97	2.63	1.57
Overall functioning
SDS - Work/school	SDS1	8.01	5.66	5.06	2.55	0.87
SDS - Social life	SDS2	7.64	5.26	5.36	2.07	0.73
SDS - Family	SDS3	7.82	5.59	5.33	2.38	0.83
SDS – Overall	SDS	23.5	16.5	15.7	7.00	2.43
SDS – Overall ≤6 (%) (remission criterion)		0.0	1.48	2.88	46.0	90.7

BDI = Beck Depression Inventory; BPI = Brief Pain Inventory; CGI-S = Clinician Global Impression of Severity; FIQ = Fibromyalgia Impact Questionnaire; N = Number of patients with available data; PGI-I = Patient Global Impression of Improvement; SF-36 = 36-item short form questionnaire; SDS = Sheehan Disability Scale.
Note: for SF-36 scores, the higher the score the better the patient’s well-being, while for all other scores, the higher the score the worse the patient’s well-being.

ISSN: 1471-2474