From: Effectiveness of tranexamic acid in reducing blood loss in spinal surgery: a meta-analysis
Studies | Number of pts (TXA/P) | Sex | Age | Weight | |||
---|---|---|---|---|---|---|---|
Male (TXA/P) | Female (TXA/P) | TXA | Placebo | TXA | Placebo | ||
Neilipovitz DT, 2001 [15] | 22/18 | 17 (12/5) | 23 (10/13) | 14.1 ± 2.1 | 13.7 ± 2.5 | 41.8 ± 16.7 | 50.6 ± 20.2 |
Sethna NF, 2005 [16] | 23/21 | 30 (17/13) | 14 (6/8) | 13.6 ± 1.8 | 14.0 ± 2.0 | 59.4 ± 18.3 | 52.4 ± 15.7 |
Wong J, 2008 [17] | 73/74 | 47 (21/26) | 100 (52/48) | 56.8 ± 16.2 | 50.0 ± 16.2 | 72.9 ± 17.2 | 73.9 ± 16.1 |
Elwatidy S, 2008 [19] | 32/32 | 39 (21/18) | 25 (11/14) | 51.56 ± 19.08 | 49.75 ± 21.04 | 72.48 ± 13.81 | 69.63 ± 17.29 |
Farrokhi MR, 2011 [18] | 38/38 | 18 (11/7) | 58 (27/31) | 45.5 ± 11.6 | 51.4 ± 11.6 | 66.6 ± 9.9 | 66.9 ± 9.4 |
Tsutsumimoto T, 2011 [20] | 20/20 | 31 (16/15) | 9 (4/5) | 68.0 ± 11.0 | 65.8 ± 11.8 | 59.6 ± 8.3 | 61.3 ± 10.2 |